Hair Anatomy and Physiology

Hair anatomy and physiology Hairs are horny filaments formed by test tube-shaped invaginations of the epidermis. The portion protruding obliquely from the skin is called the hair shaft. Inserted into the skin and extending to the subcutis is the so-called hair follicle. The hair also includes the sebaceous glands, which open into the hair funnel, … Hair Anatomy and Physiology

Metreleptin

Products Metreleptin was approved in the United States in 2014 as an injectable (Myalept). The drug is not currently registered in many countries. Structure and properties Metreleptin is a recombinant human leptin analog derived from E. coli using biotechnological methods. It differs from natural leptin in having an additional methionine at the N terminus. Metreleptin … Metreleptin

Selenium

Products Selenium is commercially available as a drug and as a dietary supplement and is included in various multivitamin preparations. As a monopreparation, it is available in the form of tablets, as a drinking solution, and as an injection preparation (e.g., Burgerstein Selenvital, Selenase), among others. Structure and properties Selenium (Se, Mr = 78.96 g/mol) … Selenium

Sulfur

Products Pure sulfur is available in pharmacies and drugstores. It is found in creams, shampoos and sulfur baths, among other products. Structure and properties The pharmacopoeia defines sulfur for external use (S, Mr = 32.07 g/mol) as a yellow powder that is practically insoluble in water. Sulfur melts at about 119°C to form a red … Sulfur

Osimertinib

Products Osimertinib was approved in the United States in 2015 and in the EU and Switzerland in 2016 in film-coated tablet form (Tagrisso). Structure and properties Osimertinib exists in the drug product as osimertinib mesilate (C28H33N7O2 – CH4O3S, Mr = 596 g/mol). It is a methylindole, aniline and pyrimidine derivative. Effects Osimertinib (ATC L01XE35) has … Osimertinib

Afamelanotide

Products Afamelanotide is administered as an implant (Scenesse, Clinuvel). It has had orphan drug status in many countries since 2008. It has not yet been registered with Swissmedic and is not approved as a drug. In the United States, the drug was approved in 2019. Structure and properties Afamelanotide is an analog of α-melanocyte-stimulating hormone … Afamelanotide

Amino acids list

Amino acids are the basic substances of proteins and there are 20 different amino acids from which the body can form many different proteins among other substances. The 20 amino acids can be divided into two groups, the essential and the non-essential amino acids. There are eight essential amino acids, isoleucine, leucine, lysine, methionine, phenylalanine, … Amino acids list

Phenylalanine | Amino acids list

Phenylalanine Like other amino acids, phenylalanine is involved in the production of other amino acids. Especially in the liver, phenylalanine can be converted to tyrosine. For this purpose, however, it must be available in sufficient quantities. Phenylalanine is also needed for the production of messenger substances such as noradrenaline. Threonine Threonine, like other essential amino … Phenylalanine | Amino acids list

Glycine | Amino acids list

Glycine Glycine can be produced in the body from other amino acids and is the smallest amino acid with a simple structure. It is a component of haemoglobin metabolism (haemoglobin transports oxygen in the blood), is involved in the energy supply in creatine metabolism and plays an important role in skin regeneration, hair formation and … Glycine | Amino acids list