Melanocortin Receptor Agonists

Bremelanotide

Products Bremelanotide was approved in the United States in 2019 as an injection solution in an auto-injector pen (Vyleesi). Structure and properties Bremelanotide (C50H68N14O10, Mr = 1025.2 g/mol) is a synthetic cyclic peptide analog of α-melanocyte stimulating hormone (α-MSH) produced in the adenohypophysis. Bremelanotide consists of seven amino acids (heptapeptide) and is an active metabolite … Bremelanotide

Afamelanotide

Products Afamelanotide is administered as an implant (Scenesse, Clinuvel). It has had orphan drug status in many countries since 2008. It has not yet been registered with Swissmedic and is not approved as a drug. In the United States, the drug was approved in 2019. Structure and properties Afamelanotide is an analog of α-melanocyte-stimulating hormone … Afamelanotide