Products Lipid-lowering agents are mainly sold as tablets and capsules as monopreparations and combination preparations. Some other dosage forms exist, such as granules and injectables. Statins have established themselves as the most important group at present. Structure and properties The chemical structure of lipid-lowering agents is inconsistent. However, within the class, groups with comparable structures … Lipid-Lowering Agents
Products Lomitapide is commercially available in capsule form (Juxtapid, Lojuxta). It was approved in the United States in 2012 and in the EU in 2013. The drug has not yet been registered in many countries. Structure and properties Lomitapide (C39H37F6N3O2, Mr = 693.7 g/mol) is present in the drug as lomitapide mesilate, a white powder … Lomitapide
Products Dirlotapide is registered as an oral solution (Slentrol). It has been approved in many countries since 2008. Structure and properties Dirlotapide (C40H33F3N4O3, Mr = 674.7 g/mol) is an indole carboxamide and biphenyl derivative. It exists as a white crystalline powder that is soluble in water to <0.1 mg/ml. Effects Dirlotapide (ATCvet QA08AB91) is an … Dirlotapide
