Products Zanamivir is commercially available as a dischaler for powder inhalation (Relenza). It has been approved in many countries since 1999. Zanamivir is far less well known than oseltamivir (Tamiflu), probably mainly because of its more complicated administration. Structure and properties Zanamivir (C12H20N4O7, Mr = 332.3 g/mol) exists as a white powder. It has a … Zanamivir
Products Neuraminidase inhibitors are commercially available in the form of capsules, powder for oral suspension, powder inhalers, and injectables. The first agents to be approved were zanamivir (Relenza) in 1999, followed by oseltamivir (Tamiflu). Laninamivir (Inavir) was released in Japan in 2010 and Peramivir (Rapivab) in the USA in 2014. The public is most familiar … Neuraminidase Inhibitor
Products Oseltamivir is commercially available as capsules and as a powder for oral suspension (Tamiflu). It has been approved in many countries since 1999. Generics were first registered in the EU in 2014 (ebilfumin) and in many countries in 2018. Structure and properties Oseltamivir (C16H28N2O4, Mr = 312.4 g/mol) is present in drugs as oseltamivir … Oseltamivir
Symptoms Flu symptoms with sudden onset: Fever, chills Muscle, joint and headache Weakness, fatigue Sore throat Dry irritating cough Especially in young children also digestive problems such as nausea, vomiting and diarrhea Other complaints (see flu) Complications The course is usually benign, mild to moderate, and self-limiting. Rarely, however, a severe and life-threatening course is … Swine Flu (Influenza A/H1N1/2009)
Products Peramivir was approved in the United States in 2014 and in the EU in 2018 as a concentrate for the preparation of an infusion solution (U.S.: Rapivab, EU: Alpivab). It has not yet been registered in many countries. Structure and properties Peramivir (C15H28N4O4, Mr = 328.4 g/mol) is present in the drug as peramivir … Peramivir
What are prodrugs? Not all active pharmaceutical ingredients are directly active. Some must first be converted to the active substance by an enzymatic or non-enzymatic conversion step in the body. These are the so-called . The term was introduced by Adrien Albert in 1958. It is estimated that up to 10% of all active ingredients … Prodrugs
Products Probenecid is commercially available in tablet form (Santuril). Santuril has been approved in many countries since 2005. Structure and properties Probenecid (C13H19NO4S, Mr = 285.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Probenecid (ATC M04AB01) inhibits tubular reabsorption of uric acid and secretion of organic anions. It thus … Probenecid
Symptoms Influenza (flu) usually begins suddenly and manifests itself in the following symptoms: High fever, chills, sweating. Muscle, limb and headache Weakness, fatigue, feeling sick. Cough, usually a dry irritating cough Rhinitis, nasal congestion, sore throat Digestive disorders such as nausea, vomiting and diarrhea, mainly in children. The flu occurs mainly in the winter months. … Flu Causes and Treatment
Products Star anise is available in pharmacies and drugstores, for example, as a powder or as whole, dried aggregate fruits. Star anise oil is also available and included in some medicines, such as gastrointestinal remedies, tea mixtures, and rubs for external use. Stem plant The evergreen tree of the star anise family (Schisandraceae) is native … Star Anise
Symptoms The possible symptoms of pneumonia include: Cough with sputum Fever, chills Headache Chest pain, pain when breathing Poor general condition: fatigue, weakness, feeling sick, confusion. Gastrointestinal disturbances such as nausea, vomiting and loss of appetite. Shortness of breath, cyanosis, difficulty breathing, increased respiratory rate. Blood pressure and pulse changes It should be noted that … Pneumonia Causes and Treatment
The active medical ingredient oseltamivir belongs to the neuraminidase inhibitor class. It is used to prevent and treat influenza flu. Side effects may include. What is oseltamivir? Oseltamivir is a drug that belongs to the class of neuraminidase inhibitors. The drug is suitable for the treatment and prophylaxis of true influenza, which is caused by … Oseltamivir: Effects, Uses & Risks
