Products Datura extracts are hardly used pharmaceutically today. Alternative medicine preparations such as homeopathics and the pure ingredients such as atropine and scopolamine are an exception. Stem plant Datura L. of the nightshade family (Solanaceae). Medicinal drug Stramonium leaves (Stramonii folium) are used as a medicinal raw material, the dried leaves or from the dried … Datura: Medicinal Uses
Products Revefenacin was approved in the United States in 2018 as a monodose inhalation solution (Yupelri). The active ingredient belongs to the LAMA group. Structure and properties Revefenacin (C35H43N5O4, Mr = 597.8 g/mol) exists as a white crystalline powder and is sparingly soluble in water. It has an active metabolite formed by hydrolysis. Effects Revefenacin … Revefenacin
Products Solifenacin is commercially available in the form of film-coated tablets (Vesicare, generics). It has been approved in many countries since 2006. Structure and properties Solifenacin (C23H26N2O2, Mr = 362.5 g/mol) is a tertiary amine and a phenylquinoline derivative that has structural similarities to atropine. It is present in drugs as (1)-(3)-solifenacin succinate, a white … Solifenacin
Products Darifenacin is commercially available in the form of sustained-release tablets (Emselex). It has been approved in many countries since 2005. Structure and properties Darifenacin (C28H30N2O2, Mr = 426.6 g/mol) is a tertiary amine. It is present in drugs as darifenacin hydrobromide, a white crystalline powder. Effects Darifenacin (ATC G04BD10) has parasympatholytic properties. It is … Darifenacin
Products In many countries, no medicines containing preparations of angel’s trumpet are on the market. Angel’s trumpets are sold as ornamental plants. Stem plant Angel’s trumpets belong to the genus and family Solanaceae. Representatives are, for example , and . The decorative plants are originally from South America. They are perennial shrubs or trees with … Angel Trumpets
Products In medicine, drugs with the active ingredient atropine are mainly used. Preparations from the leaves are less common today. In alternative medicine, belladonna is widely used, but mainly in the form of strong homeopathic dilutions. Stem plant Belladonna, a member of the nightshade family (Solanaceae), is native to Europe. The genus name is derived … Belladonna: Medicinal Uses
Products Glycopyrronium bromide is commercially available in the form of hard capsules with a powder for inhalation (Seebri Breezhaler). It was approved in the EU in 2012 and in many countries in April 2013. Glycopyrronium bromide is also combined fixed with indacaterol (Ultibro Breezhaler, approved in many countries in 2014). In 2020, a combination of … Glycopyrronium Bromide
Products LAMAs are commercially available as powders and inhalation solutions and are administered with a specially designed inhaler or with a nebulizer (nebulizer). LAMA is the acronym for , which means long-acting antagonists at muscarinic receptors. Structure and properties LAMAs are derived from the parasympatholytic atropine, which is a natural plant constituent found in various … LAMA
Products Tiotropium bromide is commercially available in the form of capsules for inhalation and has been approved since 2002 (Spiriva). The capsules are inhaled using the Spiriva HandiHaler. The inhalation solution (Spiriva Respimat) was approved in many countries in 2016. Tiotropium bromide is the successor to ipratropium bromide (Atrovent, both Boehringer Ingelheim). In 2016, a … Tiotropium Bromide
Stem plant Solanaceae, mandrake. Medicinal drug Mandragorae radix – mandrake root. Ingredients Tropane alkaloids: atropine, L-hyoscyamine, scopolamine. Effects Parasympatholytic: see under belladonna. Indications The drug is hardly used phytotherapeutically today because of its toxicity. Mandrake is used mainly in alternative medicine, for example, in homeopathy. In certain circles also as an intoxicant, hallucinogen, aphrodisiac and … Mandrake
Products Fenpipramide is commercially available in combination with levomethadone as a solution for injection for animals. It has been approved in many countries since 1962. Structure and properties Fenpipramide (C21H26N2O, Mr = 322.4 g/mol) Effects Fenpipramide (ATCvet QN02AC52) has parasympatholytic and anticonvulsant properties. Indications Fenpipramide is used in combination with levomethadone for analgesia and to … Fenpipramide
Products Scopolamine is currently sold in many countries exclusively in the form of eye drops. The transdermal patch Scopoderm TTS and other medications are no longer available. In some countries, other medicines containing scopolamine are available, such as Kwells motion sickness tablets and the Transderm Scop transdermal patch. This article refers to peroral use. In … Scopolamine
