potassium channel blockers

Antiarrhythmics

Indications For the treatment of cardiac arrhythmias. Active ingredients Class I (sodium channel blockers): class IA: Ajmaline (off-label). Quinidine (out of trade) Procainamide (out of commerce) Class IB: Lidocaine Phenytoin (not approved for this indication in many countries). Tocainide (not commercially available in many countries). Mexiletine (not on sale in many countries). Class IC: Encainid … Antiarrhythmics

Fampridine

Products Fampridine was approved in the United States in 2010, in the EU in 2011 (2017), and in many countries in 2019 in sustained-release tablet form (Fampyra). In the US, it is referred to as dalfampridine (Ampyra). Structure and properties Fampridine (C5H6N2, Mr = 94.1 g/mol) is a pyridine bearing an amino group at position … Fampridine