Potassium Channel Blockers

Amifampridine

Products Amifampridine is commercially available in tablet form (Firdapse). It has been approved in many countries since 2012. Structure and properties Amifampridine (C5H7N3, Mr = 109.1 g/mol) is present in drugs as amifampridine phosphate. It is the pyridine derivative 3,4-diaminopyridine. Amifampridine is structurally closely related to fampridine (4-aminopyridine), which is also commercially available. Effects Amifampridine … Amifampridine

Fampridine

Products Fampridine was approved in the United States in 2010, in the EU in 2011 (2017), and in many countries in 2019 in sustained-release tablet form (Fampyra). In the US, it is referred to as dalfampridine (Ampyra). Structure and properties Fampridine (C5H6N2, Mr = 94.1 g/mol) is a pyridine bearing an amino group at position … Fampridine