Proton pump inhibitors contain active ingredients that reduce the acid content in the stomach by blocking the so-called proton pump (H+/K+-ATPase). Proton pump inhibitors are certified in Germany for illnesses such as reflux disease, gastritis, ulcers in the stomach and duodenum, and a pathologically increased production of gastric acid. Frequent application finds proton pump inhibitors … Proton pump inhibitors in comparison
Review Immediately after the introduction of the drug esomeprazole, it was heavily criticized. The manufacturer stated that due to the dosage form (Nexium Mups®) and the slower metabolism (processing of the active ingredient in the liver) of the active ingredient esomeprazole, there was a considerable advantage over conventional, older drugs. This assertion should be backed … Review | Proton pump inhibitors in comparison
Proton pump inhibitors are approved in Germany and other countries for certain diseases that can be regulated by reducing stomach acid. Frequent application finds proton pump inhibitors thus with diagnoses such as stomach and intestine ulcers, stomach burn, Refluxkrankheit, Helicobacter Pylori eradications (together with antibiotics) and with a Zollinger Ellison syndrome. They are also frequently … Effect of proton pump inhibitors
Side effects As with most drugs, side effects have been described and observed with proton pump inhibitors. Common are abdominal pain and nausea, but long-term use can also cause serious illness, as well as frequent bone fractures and serious bacterial infections. The reason for this is the increase in the pH level in the gastric … Side effects | Effect of proton pump inhibitors
Side effects are generally rare when taking proton pump inhibitors (PPI). If symptoms do occur, there is usually a harmless undesirable effect behind it. Overall, side effects occur in 3-10% of patients. Side effects with short-term use It is optimal if the drug is only used for a short time. Then you can expect at … Side effects of proton pump inhibitors
Intestinal infection The higher pH value in the upper gastrointestinal tract increases the risk that certain pathogens are not killed and survive the stomach passage. This can lead to the gastrointestinal complaints mentioned above. More problematic is a so-called Clostridium difficile infection, which is characterized by severe diarrhea and abdominal cramps. There are first indications … Intestinal infection | Side effects of proton pump inhibitors
