Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban
Pulmonary embolism is a common clinical picture. Although the statements in various studies differ, it can be assumed that on average about 1 person per 1000 inhabitants is affected by pulmonary embolism in Germany each year – older people more often than younger people. Among hospitalized patients, pulmonary embolism is one of the most common … Pulmonary Embolism: Life-threatening Clot
The following groups of people are at higher risk of developing pulmonary embolism: Bedridden and immobile people are particularly at risk for venous thrombosis and, consequently, pulmonary embolism. After surgery, the risk for thrombosis is very high; if the affected person then stands up or presses hard during defecation, a clot can detach and reach … Pulmonary Embolism: Symptoms and Diagnosis
Pulmonary embolism must always be treated in the hospital. The first step in the treatment of pulmonary embolism: the patient must first remain on bed rest. As a basic measure of therapy, the physician administers painkillers and sedatives as well as oxygen, and possibly also substances that stabilize the circulation. Treatment with medications He injects … Pulmonary Embolism: Therapy and Course
Every human and animal cell is enveloped by a semipermeable membrane. It protects the cell interior against harmful influences from the outside, and it is responsible for the necessary exchange of substances from the outside to the inside as well as from the inside to the outside. In a third function, the membrane takes over … Cell Membrane: Structure, Function & Diseases
Blood vessels run through the entire human body as proverbial lifelines. Two different types of vessels are distinguished, namely arteries and veins. See also: blood circulation. What are veins? Veins are vessels that carry blood to the heart, as opposed to arteries, which carry it to the periphery. There is less pressure inside veins than … Veins: Structure, Function & Diseases
Weakness of the veins, venous insufficiency or venous disease is declared as a widespread disease and can occur at a fairly young age. However, vein weakness does not necessarily have to be a typical age-related disease. In addition, vein disease can be well prevented. What is venous insufficiency Venous weakness (venous disease) is manifested by … Venous Insufficiency (Vein Disease): Causes, Symptoms & Treatment
A thrombosis or blood clot is a disorder or blockage of a blood vessel. Most commonly, thrombosis occurs in the legs or veins of older people after long periods of sitting or lack of exercise. What is thrombosis? Thrombosis is a vascular disease in which a thrombus (blood clot) forms in a blood vessel. Thrombosis … Thrombosis: Causes, Symptoms & Treatment
Products Streptokinase was commercially available as an injectable in many countries (Streptase, off label). It is still available in other countries. Structure and properties Streptokinase is a protein derived from group C hemolytic streptococci. Effects Streptokinase (ATC B01AD01) has fibrinolytic and thrombolytic properties. It combines with plasminogen to form a streptokinase-plasminogen complex. This complex converts … Streptokinase
Effects Fibrinolytic: dissolve fibrin Thrombolytic: dissolve thrombi Indications For the treatment of thrombosis and embolism: Myocardial infarction Ischemic stroke Deep vein thrombosis Pulmonary embolism Acute and subacute thrombosis Arterial occlusive diseases Agents Alteplase (Actilyse) Urokinase (Urokinase HS medac) Reteplase (Rapilysin, out of trade) Streptokinase (streptase, out of trade) Tenecteplase (metalysis)
Academic pathophysiology is a medical subfield within pathology. It deals with the study of pathologically altered bodily functions (pathology) as well as the changes in the body (physiology) of a living being. The medical term goes back to the Greek language. Pathos means suffering and physis means body and nature. What is pathophysiology? Pathophysiology deals … Pathophysiology: Treatment, Effects & Risks
Definition Pulmonary embolism is one of the most common causes of death during pregnancy. Pulmonary embolism is the occlusion of one or more pulmonary vessels by a blood clot (thrombus). The circulatory disorder hinders the exchange of oxygen in the lung tissue and patients suffer from severe shortness of breath. The risk of pulmonary embolism … Pulmonary embolism in pregnancy
