Leukotriene Synthesis Inhibitors

Effects

Leukotriene synthesis inhibitors are antiallergic and anti-inflammatory.

Mechanism of action

Inhibition of the synthesis of leukotrienes from arachidonic acid by inhibition of 5-lipoxygenase.

Indications

For prevention and long-term therapy of asthma in adults and children over 12 years of age.

Active ingredients

  • Zileuton (USA: Zyflo) – not commercially available in many countries.