Rheumatoid Arthritis Causes and Treatment

Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment

COVID-19

Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19

Tocilizumab

Products Tocilizumab is commercially available as a concentrate for the preparation of an infusion solution and as a solution for injection in a prefilled syringe and in a prefilled pen (Actemra, RoActemra in some countries). It has been approved in many countries since 2008. Structure and properties Tocilizumab is a recombinant humanized IgG1 monoclonal antibody … Tocilizumab

Immunosuppressants

Products Immunosuppressants are commercially available in numerous dosage forms, for example, as creams, ointments, tablets, capsules, solutions, eye drops, and injectables. Structure and properties Within immunosuppressants, several groups can be identified. These include steroids such as the glucocorticoids, substances of microbiological origin such as ciclosporin and mycophenolate mofetil, derivatives of nucleic acids and their components … Immunosuppressants

Sarilumab

Products Sarilumab was approved in the United States and EU in 2017 and in many countries in 2018 as a solution for injection (Kevzara, prefilled syringe, prefilled pen). Structure and properties Sarilumab is a human IgG1 monoclonal antibody with a molecular mass of 150 kDa. It is produced by biotechnological methods. Effects Sarilumab (ATC L04AC14) … Sarilumab