Semaglutide for Weight Loss & Diabetes

What is semaglutide and how does it work? Semaglutide mimics the body’s own hormone glucagon-like peptide (GLP-1) and binds to its docking sites (receptors). The active ingredient therefore belongs to the group of GLP-1 receptor agonists, or GLP-1-RA for short. Semaglutide causes the pancreas to produce and release more insulin. As a result of the … Semaglutide for Weight Loss & Diabetes

GLP-1 Receptor Agonists

Products The first agent in the GLP-1 receptor agonist group to be approved was exenatide (Byetta) in the United States in 2005 and in many countries and the EU in 2006. In the meantime, several other drugs have been registered (see below). These drugs are also known as incretin mimetics. They are commercially available as … GLP-1 Receptor Agonists

Liraglutide

Products Liraglutide was approved in many countries in 2009 as a solution for injection in a prefilled pen (Victoza). In 2014, a fixed-dose combination with insulin degludec was released (Xultophy); see IDegLira. In 2016, Saxenda was registered for the treatment of overweight and obesity. Its related successor, semaglutide, unlike liraglutide, only needs to be injected … Liraglutide

Semaglutide

Products Semaglutide was approved in the US and EU in 2017 and in many countries in 2018 as a solution for injection (Ozempic). The agent is structurally and pharmacologically related to liraglutide (Victoza), which, unlike semaglutide, is injected once daily (both Novo Nordisk). In 2019, tablets containing semaglutide were approved for the first time in … Semaglutide