Laxative

Products Laxatives are available in numerous dosage forms. These include, for example, tablets, drops, suppositories, powders, granules, solutions, syrups and enemas. Structure and properties Laxatives do not have a uniform chemical structure. However, groups can be identified (see below). Effects Laxatives have laxative properties. They stimulate bowel emptying by different mechanisms depending on the active … Laxative

Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

Bisacodyl

Products Bisacodyl is commercially available in the form of enteric-coated tablets (dragées) and suppositories (Dulcolax, generics). It has been approved in many countries since 1957. Structure and properties Bisacodyl (C22H19NO4, Mr = 361.39 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a diphenylmethane and triarylmethane derivative. Bisacodyl is … Bisacodyl

Sodium Picosulfate

Products Sodium picosulfate is commercially available in the form of tablets, soft capsules (pearls), and drops (e.g., Laxoberon, Dulcolax Picosulfate). It has been approved in many countries since 1973. Structure and properties Sodium picosulfate (C18H13NNa2O8S2, Mr= 481.41 g/mol) is structurally closely related to bisacodyl. The difference is that it is esterified with sulfuric acid instead … Sodium Picosulfate

Medication Overuse

Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse

Phenolphthalein

Products Phenolphthalein has been included in many laxatives in the past, for example in Reguletts tablets (100 mg) in many countries. Sales of the last drug containing phenolphthalein (Paragar Emulsion) will be discontinued in many countries in 2018. Structure and properties Phenolphthalein (C20H14O4, Mr = 318.3 g/mol) exists as a white powder that is practically … Phenolphthalein