Products Somatropin is commercially available as an injectable from several manufacturers. Recombinant growth hormone has been available since the late 1980s. Biosimilars are approved in some countries. Structure and properties Somatropin is a recombinant polypeptide hormone with a molecular mass of 22 kDa, consisting of 191 amino acids. It corresponds to human growth hormone from … Somatropin
Products Octreotide is commercially available as an injectable (Sandostatin, Sandostatin LAR, generics). It has been approved in many countries since 1988. Structure and properties Octreotide is a synthetic octapeptide derivative of the hormone somatostatin. It is present in the drug as octreotide acetate and has the following structure: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol, xCH3COOH (x = 1.4 to 2.5). … Octreotide
Products Pegvisomant is commercially available as a powder and solvent for the preparation of a solution for injection (Somavert). It has been approved in many countries since 2005. Structure and properties Pegvisomant is a derivative of human growth hormone produced by biotechnological methods. It consists of 191 amino acids and is pegylated at several sites. … Pegvisomant
Products Therapeutic proteins are usually administered in the form of injection and infusion preparations and must be stored in a refrigerator. The first recombinant protein to be approved was human insulin in 1982. Some proteins, for example, are also available in tablet, capsule, and powder form and can be stored at room temperature, such as … Therapeutic Proteins
Products Doping agents include approved drugs, legal and illegal intoxicants, experimental agents, and illegally manufactured and trafficked substances. Doping includes non-drug doping methods, such as blood doping, in addition to drugs. Effects Doping agents differ in their pharmacological activities. Stimulants, for example, stimulate and thus increase alertness and aggressiveness for competition. In contrast, beta-blockers provide … Doping in Competitive Sports
Products Biosimilars are copycat preparations of biotechnology-derived drugs (biologics) that have strong similarities to the originator drugs but that are not exactly the same. The similarity relates to biological activity, structure, function, purity and safety, among other things. Biosimilars differ from generics of small molecule drugs in important ways. Biosimilars are usually marketed as injection … Biosimilars
Symptoms Possible symptoms include burning pain and sensory disturbances of the fingers, such as numbness, tingling, and falling asleep. Patients’ hands “go to sleep” and they respond by shaking and massaging them. The complaints often occur at night and affect the inside of the thumb, the index finger, the middle finger and half of the … Carpal Tunnel Syndrome Causes and Treatment
Products Lanreotide is commercially available as a solution for injection (Somatuline Autogel). It has been approved in many countries since 2004. Structure and properties Lanreotide is present in the drug as lanreotide acetate. It is a synthetic octapeptide analog of somatostatin with the following structure: D-βNal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2, x(CH3COOH), where x = 1 to 2 Effects Lanreotide … Lanreotide
Many children today suffer from the consequences of lack of exercise and poor nutrition at an early age. Yet physical activity is enormously important for healthy development right from the start. But how can we motivate our little ones to do sports and steer their urge to move in the right direction? Practice makes perfect … Sports and Exercise: Educating Children To Lead an Active Lifestyle
Somatotropin, also called somatropin, growth hormone, or somatotropic hormone, is a so-called peptide hormone that is produced in the anterior pituitary gland. The hormonal action of somatotropin affects overall metabolism and growth. What is somatropin? Schematic diagram showing the anatomy and structure of the endocrine (hormone) system. Click to enlarge. Like most hormones in the … Somatropin: Function & Diseases
Somatotropic hormone, somatropin, growth hormoneSTH or GH Definition Somatotropin is a hormone produced in the human body that influences and promotes growth and metabolism. It is water-soluble and consists of 191 amino acids. Somatotropin is produced in the pituitary gland of the human brain, more precisely in the so-called “anterior pituitary gland“. As an important … Somatotropin
Non-medical use of somatotropin The non-medical use of somatotropin is becoming increasingly popular in Germany. The target groups vary greatly depending on the desired effect. The non-medical benefits of Somatotropin have long since ceased to be of interest only to bodybuilders. Muscle building is only one of the desired effects of the hormone. A particularly … Non-medical use of somatotropin | Somatotropin
