Products Ezetimibe is commercially available in tablet form, as a monopreparation (Ezetrol, generic), and as a fixed combination with simvastatin (Inegy, generic) and with atorvastatin (Atozet). Also released is a combination with rosuvastatin. Ezetimibe was approved in many countries and in the United States in 2002. Generic and auto-generics entered the market in November 2017. … Ezetimibe
Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin
Products Red mold rice is commercially available in some countries as a dietary supplement or food. In 2014 and 2019, Swissmedic informed that the sale of products with is not allowed in many countries, either as medicines or dietary supplements. Ingredients Red mold rice is a fermentation product of rice with mold strains of the … Red Mold Rice
Products Fluvastatin is commercially available in the form of capsules and sustained-release generic tablets (generics). It has been approved in many countries since 1993. Sales of the original Lescol were discontinued by Novartis in 2018. Structure and properties Fluvastatin (C24H26FNO4, Mr = 411.5 g/mol) is present in drugs as fluvastatin sodium, a white or pale … Fluvastatin
Products Bempedoic acid was approved in the EU, the United States, and many countries in 2020 in the form of film-coated tablets (Nilemdo). The active ingredient is also combined fixed with ezetimibe (Nustendi film-coated tablets). Structure and properties Bempedoic acid (C19H36O5, Mr = 344.5 g/mol) exists as a white crystalline powder that is practically insoluble … Bempedoic Acid
What is cholesterol esterase? Cholesterol esterases are enzymes that are responsible for the cleavage of cholesterol ester compounds. Cholesterol esters are composed of cholesterol and fatty acids. These are connected to each other by a certain type of bond, a so-called esterification. During the cleavage process, free cholesterol and fatty acids are created, which are … Cholesterol esterase – It is important for this!
What are the standard values of cholesterol esterase? A blood sample is needed to determine the level of cholesterol esterase. In this sample the amount can be measured in a medical laboratory. In a healthy person it is between 3,000 and 8,000 IU per liter. “IU” stands for international units and represents a quantity defined … What are the standard values of cholesterol esterase? | Cholesterol esterase – It is important for this!
Vitamin B3 is nicotinic acid, also known as niacin, which was discovered as early as 1867. Its effectiveness in the physiology of living things was not known until nearly a century later in 1934. Mode of action of vitamin B3 In nature, there are numerous suppliers of vitamin B3. For example, game or fish, but … Vitamin B3: Function & Diseases
In medicine, statin belongs to the pharmacological substance class 3 of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (HMG-CoA reductase). HMG-CoA is an intermediate in cholesterol synthesis in humans, which is why statins are used to lower cholesterol in dyslipidemia. What is statin? Statins are so-called CSE inhibitors and thus lead to a reduction in blood cholesterol … Statin: Effects, Uses & Risks