Products Medicines containing tacrine are no longer available in many countries. Cognex capsules are no longer on the market. Structure and properties Tacrine (C13H14N2, Mr = 198.3 g/mol) is a tetrahydroacridin-9-amine. It is present in drugs as tacrine hydrochloride monohydrate. Effects Tacrine (ATC N06DA01) is indirectly parasympathomimetic. Effects are due to central and reversible inhibition … Tacrine
Symptoms Alzheimer’s disease manifests itself in a continuously progressive loss of memory and mental and cognitive abilities. Possible symptoms of the disease include: Disorders and loss of memory. Initially, mainly short-term memory is affected (learning new things), later long-term memory is also affected. Forgetfulness, confusion Disorientation Speech, perception and thinking disorders, motor disorders. Personality change, … Alzheimer’s
Products Procyclidine is commercially available in tablet form (Kemadrin). It has been approved in many countries since 1956. Structure and properties Procyclidine (C19H29NO, Mr = 287.4 g/mol) has structural similarities to biperides. Effects Procyclidine (ATC N04AA04) has anticholinergic properties and is effective against rigor, tremor, akinesia, speech and writing disorders, gait unsteadiness, increased salivation, sweating, … Procyclidine
Products Parasympathomimetics are commercially available in the form of tablets, capsules, solutions, transdermal patches, injectable solutions, and eye drops, among others. Structure and properties Many parasympathomimetics are structurally related to the natural ligand acetylcholine. Effects Parasympathomimetics have cholinergic (parasympathomimetic) properties. They promote the effects of the parasympathetic nervous system, a portion of the autonomic nervous … Parasympathomimetics