tenecteplase

Fibrinolytics

Effects Fibrinolytic: dissolve fibrin Thrombolytic: dissolve thrombi Indications For the treatment of thrombosis and embolism: Myocardial infarction Ischemic stroke Deep vein thrombosis Pulmonary embolism Acute and subacute thrombosis Arterial occlusive diseases Agents Alteplase (Actilyse) Urokinase (Urokinase HS medac) Reteplase (Rapilysin, out of trade) Streptokinase (streptase, out of trade) Tenecteplase (metalysis)

Tenecteplase

Products Tenecteplase is commercially available as an injectable (metalysis). The drug has been approved in many countries since 2000. Structure and properties Tenecteplase is a recombinant fibrin-specific plasminogen activator produced by biotechnological methods. The glycoprotein consists of 527 amino acids. The sequence is modified from native tissue-specific plasminogen activator (t-PA) at three sites. Effects Tenecteplase … Tenecteplase