Products Scabi-med cream containing 5% permethrin was approved in many countries in 2018. For the years prior to that, no finished drug product was registered for the treatment of scabies in many countries following the cessation of sales of Eurax (crotamiton). In other countries, however, the cream had been available for years or even decades. … Permethrin Cream
Symptoms Sunburn manifests itself as an extensive reddening of the skin (erythema), as a 1st degree burn with pain, burning, itching, tightening of the skin and, in severe cases, additionally with skin blisters (transition to a 2nd degree burn). It develops continuously over several hours and reaches a maximum after 12 to 24 hours. The … Sunburn Causes and Remedies
Symptoms Nummular eczema (from Latin , coin) is an inflammatory skin disease that manifests itself in sharply defined, coin-shaped rashes that primarily affect the extensor sides of the legs, arms, and trunk. The areas are weeping, inflamed (reddened), and may become dry, crusted, and itchy. Unlike cutaneous fungus, the lesions are filled in and do … Nummular Eczema
Products Cortisone mixed ointments are not commercially available as finished drug products. They are prepared in pharmacies as extemporaneous preparations. Usually, a cream or ointment containing cortisone is diluted by mixing it with an ingredient-free base, such as Excipial or Antidry. The concentration of the glucocorticoid decreases in the process. However, the risk for adverse … Cortisone Mixed Ointments
Symptoms Nasal polyps are usually bilateral and localized benign mucosal protrusions of the nasal cavity or sinuses. The leading symptom is nasal constriction leading to a change in voice quality. Other possible symptoms include a watery discharge (rhinorrhea), impaired sense of smell and taste, pain and a feeling of fullness in the head. Nasal polyps … Nasal Polyps
Products Methylprednisolone is commercially available as an ointment, fatty ointment, cream, in tablet form, and as an injection and infusion preparation (e.g., Medrol, generics). Structure and properties Methylprednisolone (C22H30O5, Mr = 374.5 g/mol) Effects Methylprednisolone (ATC D07AA01, ATC D10AA02, ATC H02AB04) is anti-inflammatory, antiallergic, and immunosuppressive.
Products Methylprednisolone aceponate has been approved in many countries since 1991 and is commercially available as cream, ointment, and fatty ointment (Advantan). Structure and properties Methylprednisolone aceponate (C27H36O7, Mr = 472.6 g/mol) is a lipophilic and nonhalogenated glucocorticoid that is hydrolyzed in the skin by esterases to the active metabolite 6α-methylprednisolone-17-propionate. Effects Methylprednisolone aceponate (ATC … Methylprednisolone Aceponate
Symptoms Usually beginning before the age of 20, the appearance of white patches is completely asymptomatic; the foci themselves exhibit neither itching nor scaling, are often bizarrely configured, and occasionally have darker pigmentation around the edges. A hereditary predisposition exists in one third (approx. 35%) of affected individuals. The spread is extremely variable, it can … Vitiligo (White Spot Disease)
Symptoms Cradle cap often occurs in infants during the first months of life. It manifests as a yellowish, encrusted, greasy and scaly scalp and may be accompanied by redness. The rash is not itchy and does not pose a medical problem for the child. Redness may also occur around the eyes, on the neck, and … Cradle Cap
Products Halcinonide was commercially available as a solution, cream, and fat cream, and was also combined fixedly with urea and salicylic acid (Betacorton, Betacorton S). It was approved in many countries in 1981. It was discontinued from 2018 to 2019. Structure and properties Halcinonide (C24H32ClFO5, Mr = 454.96 g/mol) exists as a white powder that … Halcinonide
Products Halometasone is commercially available as a cream in combination with triclosan (Sicorten plus). It has been approved in many countries since 1983. Structure and properties Halometasone (C22H27ClF2O5, Mr = 444.9 g/mol) is a chlorinated and fluorinated (halogenated) steroid. Effects Halometasone (ATC D07AC12) has anti-inflammatory, antiallergic, and immunosuppressive properties. It is a potent class III … Halometasone
Products Diflucortolone valerate has been commercially available in many countries since 1980 as a cream in fixed combination with the azole antifungal isoconazole (Travocort). Structure and properties Diflucortolone valerate (C27H36F2O5, Mr = 478.6 g/mol) Effects Diflucortolone valerate (ATC D07AC06) has anti-inflammatory, antiallergic, immunosuppressive, and antipruritic properties. Indications In many countries, diflucortolone valerate is marketed exclusively … Diflucortolone Valerate