Quinolone

Products The first active ingredient in the quinolone group to be introduced was nalidixic acid in 1967 (NegGram). It is no longer commercially available in many countries. Other drugs are available today (see below). Various dosage forms are available, for example, film-coated tablets, oral suspensions, eye drops, ear drops, and infusion solutions. Due to adverse … Quinolone

Trovafloxacin

Products Trovafloxacin was commercially available in many countries as film-coated tablets and as an infusion concentrate (Trovan, Pfizer). It was withdrawn from the market in 1999 because of potential adverse effects. Structure and properties Trovafloxacin (C20H15F3N4O3, Mr = 416.4 g/mol) is a fluoronaphthyridone. It is present in tablets as trovafloxacin mesilate. In parenteral dosage forms, … Trovafloxacin