venous thrombosis pelvic vein thrombosis

Pentasaccharide FondaparinuxArixtra® | Drug-induced thrombosis prophylaxis

Pentasaccharide FondaparinuxArixtra® The pentasaccharide fondaparinux (Arixtra®) is a synthetically produced 5-sugar that inhibits factor Xa in the coagulation cascade via antithrombin (a naturally occurring blood clotting inhibitor in the body). The drug is administered by subcutaneous administration (subcutaneously, see c.). Once absorbed into the bloodstream, it binds to antithrombin. The substance is excreted via the … Pentasaccharide FondaparinuxArixtra® | Drug-induced thrombosis prophylaxis

Homeopathic remedies | Drug-induced thrombosis prophylaxis

Homeopathic remedies Although homeopathic remedies are not suitable for the sole prophylaxis of thrombosis, they can also help to reduce the risk of thrombosis before and after surgery if the risk factors are low. Suitable remedies include Lachesis, horse chestnut and witch hazel (witch hazel). You can read more information on this topic here: Homeopathy … Homeopathic remedies | Drug-induced thrombosis prophylaxis

Start and duration of thrombosis prophylaxis

Note General information on the topic of thrombosis prophylaxis can be found on the homepage on the topic: Thrombosis prophylaxis Start of prophylaxis The start of thrombosis prophylaxis should be as early as possible to the risk-causing situation. Nowadays, thrombosis prophylaxis is routinely performed in inpatient surgical departments both peri- and postoperatively, usually until discharge. … Start and duration of thrombosis prophylaxis

Primary hemostasis and platelet function | Start and duration of thrombosis prophylaxis

Primary hemostasis and platelet function The aim of primary hemostasis is to stop bleeding by forming a platelet (thrombus). The platelets are naturally involved in this process, as are a number of different factors (e.g. von Willebrand factor) and receptors. If, for example, a blood vessel is injured, it contracts in the primary reaction (vasoconstriction) … Primary hemostasis and platelet function | Start and duration of thrombosis prophylaxis

Thrombosis prophylaxis

Synonyms in a broader sense Thromboembolism prophylaxis Thrombosis protection Thrombosis prevention Thrombosis Blood Clot Embolism Definition and introduction In thrombosis prophylaxis, a distinction is made between physical and medicinal measures. The physical measures include : In drug intervention, a number of different drugs are available to reduce the blood‘s tendency to clot. The points of … Thrombosis prophylaxis

Secondary Hemostasis | Thrombosis prophylaxis

Secondary Hemostasis For permanent closure, the plug must be replaced by a fibrin thrombus. For this purpose, the fibrinogen (or factor I of the blood clotting cascade), which occurs in an inactive precursor in the blood, must be converted to fibrin. This requires a staggered activation of different clotting factors in the blood. This preceding … Secondary Hemostasis | Thrombosis prophylaxis

Pregnancy | Thrombosis in the leg

Pregnancy Pregnancy and puerperium are factors that greatly increase the risk of developing thrombosis in the leg. In fact, thrombotic diseases are the most common cause of death during pregnancy and shortly after birth. This results from the hormonal changes in the body during pregnancy. Pregnancy hormones, such as progesterone, dilate the veins so that … Pregnancy | Thrombosis in the leg

Thrombosis in the leg

Synonyms thrombus, blood clot, blood clot Definition A thrombosis is a blood clot that forms in the body’s venous system, closes a blood vessel and prevents venous blood flow to the affected area. Thromboses often occur in the deep veins of the legs and pelvis, less frequently in arm veins. Introduction Thrombi that develop in … Thrombosis in the leg

Causes | Thrombosis in the leg

Causes There are three main factors that cause thromboses in the leg, which are summarized under the name Virchow Trias. These include changes in the inner walls of blood vessels, changes in blood flow and disturbances in the composition of the blood. Vascular walls change in connection with injuries, when scars are formed and through … Causes | Thrombosis in the leg

The Pill | Thrombosis in the leg

The Pill The most risky of all contraceptive pills is the combined preparation of estrogen and progestin, because it contains the substance drospirenone. Studies have shown that it carries the greatest risk of thrombosis. It is statistically interesting that only 3-6 out of 10,000 women are affected. Smoking increases the risk of thrombosis, as do … The Pill | Thrombosis in the leg

Therapy | Thrombosis in the leg

Therapy Thromboses in the leg indicate that blood clots no longer dissolve properly. Therapeutically, therefore, substances are generally used to reactivate this mechanism. Heparin is the agent of choice here, it prevents the formation of further thromboses. To dissolve the thrombosis in the leg, a recanalization can also be performed. In this procedure, the vein … Therapy | Thrombosis in the leg

Consequences of a thrombosis in the leg | Thrombosis in the leg

Consequences of a thrombosis in the leg By far the most feared consequence of a thrombosis in the leg is pulmonary embolism. It occurs when the thrombus loses its adhesion to the vessel wall and is transported with the bloodstream into the lung, where it closes an artery. This occurs when the leg is moved, … Consequences of a thrombosis in the leg | Thrombosis in the leg