Laboratory parameters of the 1st order – obligatory laboratory tests.
- Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, if necessary urine culture (pathogen detection/bacteria and shoot fungi, if necessary mycoplasma, ureaplasma urealyticum and resistogram).
Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.
- Urethral smear (smear from the urethra) for pathogens:
- Direct microscopy with Gram and methylene blue staining [diagnosis of gonococcal infection]Note: Creation of a culture for resistance determination.
- Bacteria and fungi, if necessary mycoplasma (M. genitalium), Ureaplasma urealyticum T. vaginalis as well as Chlamydia trachomatis and Neisseria gonorrhoeae; if necessary also Chlamydia trachomatis DNA detection (Chlamydia trochmatis-PCR) or Neisseria gonorrhoeae DNA detection (Go-PCR, gonococcal PCR; DNA detection using NAAT).
- Urine (first beam): NAAT (nucleic acid amplification test) for the detection of chlamydial infection [only in men; in women, however, from the urethral swab].
- Urine cytology
- Small blood count
- CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
- Urea, creatinine, cystatin C or creatinine clearance, if necessary.
Bold: the three most common causative agents of urethritis.