The following symptoms and complaints may indicate Werlhof disease:
Leading symptoms
- Petechiae – minute skin/mucosal hemorrhages (flea-like); often first on the ankles, lower legs
Associated symptoms
- Epistaxis (nosebleed)
- Gum bleeding
- Menorrhagia – prolonged and increased menstruation (menstrual bleeding).
- Gastrointestinal bleeding
- Intracranial hemorrhage (ICB; cerebral hemorrhage).
These symptoms usually do not occur until the platelet concentration is <30,000/μl.
