What are the long-term consequences of a folic acid overdose? | What happens if I overdose of folic acid?

What are the long-term consequences of a folic acid overdose?

Serious dangers cannot occur through the intake of natural folic acid, as it is difficult to absorb folic acid in very large quantities through food. Synthetically produced folic acid, which is available as a food supplement, can be absorbed much better by the body. Here the risk of health damage has not yet been finally clarified.

It is assumed that an overdose of folic acid over a long period of time influences cell division. Some scientists suspect that under certain circumstances the risk of cancer may increase due to an overdose of folic acid over many years. One study has shown that the risk of breast cancer could possibly increase. Furthermore, it is estimated that the risk of colorectal cancer is also increased by an overdose over many years. In addition, a hidden vitamin B12 deficiency due to folic acid overdose may result in consequential damage, such as nerve damage.

Is this reversible?

As a rule, the symptoms recede after a normalization of the folic acid intake. It is unclear what the possible increased risk of cancer is, as research in this area is not yet sufficient to make reliable statements. If a vitamin B12 deficiency has been masked by an overdose of folic acid and this has led to nerve damage, this may be partially reversible. Especially if they have been present for a long time, they may continue to exist even after the deficiency has been successfully compensated.