What other drugs increase the damage to the liver antibiotics? | Painkillers for diseases of the liver

What other drugs increase the damage to the liver antibiotics?

Most antibiotics can also be taken for liver diseases after consulting the doctor, as they are nevertheless well tolerated. However, there are some exceptions such as Cotrimoxazol. This antibiotic should not be taken in cases of minor liver and kidney damage.

Caution is also required with most antidepressants, as they are broken down with a delay in liver failure and the effect can thus change. In case of an existing liver disease the dose of the medication may have to be adjusted by the doctor to avoid side effects. This also applies to drugs from the group of tricyclic antidepressants (e.g. Imipramin-neuraxpharm).

• One example is fluoxetine, an antidepressant from the group of selective serotonin reuptake inhibitors, which is very often prescribed for depression or obsessive-compulsive disorders.

There are some active substances in the group of antihistamines that require caution in the case of severe liver dysfunction. For example, when taking Loratadine, the doctor treating the patient should be consulted. This also applies to terfenadine, which is an absolute contraindication in the case of significantly impaired liver function.

In the case of beta-blockers, the dosage of a few drugs must be adjusted in the event of acute liver damage. Examples are metoprolol or Inderal from the group of beta-adrenergic antagonists. Loperamide or Imodium are motility inhibitors that are taken for the symptomatic treatment of diarrhea. In patients with impaired liver function they should be taken with caution and patients should be closely monitored for CNS damage. Again, as with any medication for existing liver disease, the use of these drugs should be clarified in advance with a physician.

What can I do to minimize the damage of painkillers to the liver?

Almost all drugs are broken down by the liver, which makes it difficult to choose the right painkiller for a liver disease. Nevertheless, toxic liver damage is very rare when taken in the right dosage. Nevertheless, liver disease should always be examined by a specialist and the treatment options discussed.

If you feel that you have not dosed a painkiller correctly or if you show signs of drug intoxication, you should consult a doctor immediately.

• In any case, it is important to consult your doctor so that the dose can be adjusted individually and overdose can be avoided.
• You should also always read the package insert of the medication carefully and also pay attention to interactions with other medications. Some painkillers should not be combined with other preparations, including natural remedies.
• Furthermore, factors such as obesity or alcohol consumption worsen the liver values.

  With an existing liver illness one should pay attention thus absolutely to the correct and healthy nutrition and do without alcohol.

• The use of homeopathic remedies, such as milk thistle, is also discussed in the literature. Milk thistle protects the liver and helps to alleviate liver disorders and liver weakness. It is also used to treat alcohol and medication poisoning and can have a positive effect on the damage to the liver caused by painkillers.