The following are the most important diseases or complications that may be contributed to by Zollinger-Ellison syndrome:
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Hyperparathyroidism (MEN-independent).
- Hypokalemic metabolic alkalosis
Mouth, esophagus (food pipe), stomach and intestines (K00-K67; K90-K93).
- Bleeding of an ulcer – gastric ulcers (ulcus ventriculi) and duodenal ulcers (ulcus duodeni), sometimes in the jejunum (atypical localization).
- Dysbiosis (imbalance of the intestinal flora).
- Esophagitis (inflammation of the esophagus)
- Perforation of an ulcer – opening of the ulcer.
Neoplasms – tumor diseases (C00-D48)
- Metastatic gastrinoma