The following are the most important diseases or complications that may be contributed to by spinal muscular atrophy:
Respiratory system (J00-J99)
- Aspiration pneumonia – pneumonia caused by inhalation of foreign substances (in this case, stomach contents).
- Pneumonia (pneumonia)
- Respiratory insufficiency – isolated arterial hypoxemia (oxygen deficiency) with reduction of partial pressure of oxygen below a threshold of 65-70 mmHg with normal to reduced carbon dioxide.
Endocrine, nutritional and metabolic diseases (E00-E90).
- Obesity
- Endocrine dysfunctions
Cardiovascular system (I00-I99)
- Coronary artery disease (CAD; coronary artery disease).
- Heart failure (cardiac insufficiency)
- Hypotension (low blood pressure)
- Cardiomyopathy (heart muscle disease)
- Lymphedema -increase in tissue fluid caused by damage to the lymphatic system.
Esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Gastronintestinal dysfunctions (disorders of gastrointestinal function).
Musculoskeletal system and connective tissue (M00-M99).
- Scoliosis – lateral curvature of the spine.
- Joint contractures (joint stiffness).
Psyche – nervous system (F00-F99; G00-G99)
- Anxiety disorders
- Autonomic dysfunction/dysfunction associated with orthostatic intolerance and hypotension (low blood pressure)
- Depression
- Insomnia (sleep disorder)
- Obsessive-compulsive disorder
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
