Products
Buflomedil is no longer available as a drug in many countries. Loftyl is out of commerce.
Structure and properties
Buflomedil (C17H25NO4, Mr = 307.4 g/mol) exists as a white, microcrystalline powder that is readily soluble in water.
Effects
Buflomedil (ATC C04AX20) is vasoactive and α-adrenolytic. It inhibits platelet aggregation, improves erythrocyte deformability and regional partial pressure of oxygen.
Indications
Arterial circulatory disorders, angioneuropathies (Raynaud’s disease, acrocyanosis), microangiopathies with trophic disturbances due to chronic arterial insufficiency.
