Corneal Ulcer: Causes

Pathogenesis (development of disease)

Corneal ulcer (corneal ulcer) is often a complication of keratitis (inflammation of the cornea).

Etiology (causes)

Behavioral causes

  • Wearing of contact lenses

Disease-related causes

Eyes and eye appendages (H00-H59).

  • Keratitis (corneal inflammation), unspecified [bacteria (eg, Staphylococcus aureus, Streptococcus pneumoniae), viruses (herpes simplex), mycoses (especially after antibiotic therapy, or glucocorticoid eye drops), parasites (eg. E.g., amoebae (amoebic keratitis); mostly indirectly via contaminated contact lens cases and care products or subsequently contaminated contact lenses); chemical, physical, mechanical; neurological]
  • Decreased/restricted eyelid closure or lack of eyelid closure in facial nerve palsy – leads to drying of the eye.

Endocrine, nutritional and metabolic diseases (E00-E90).

  • Vitamin A deficiency

Injuries, poisoning, and other consequences of external causes (S00-T98).

  • Minor injuries
  • Corneal foreign bodies
  • Wearing contact lenses