Delirium: Or something else? Differential Diagnosis

Respiratory System (J00-J99)

  • Pulmonary insufficiency with hypoxemia (decreased blood oxygen content) and hypercapnia (increased blood carbon dioxide content).
  • Pneumonia (inflammation of the lungs)

Blood, blood-forming organs – immune system (D50-D90).

Endocrine, nutritional and metabolic diseases (E00-E90).

  • Dehydration (lack of fluid).
  • Diabetic ketoacidosis – severe metabolic derailment (ketoacidosis) due to insulin deficiency.
  • Folic acid deficiency
  • Hyperglycemia (high blood sugar)
  • Hypercalcemia (excess calcium)
  • Hypernatremia (excess sodium)
  • Hyperparathyroidism (parathyroid hyperfunction).
  • Hyperthyroidism (hyperthyroidism)
  • Hypoglycemia (low blood sugar)
  • Hypocalcemia (calcium deficiency)
  • Hypomagnesemia (magnesium deficiency)
  • Hypoparathyroidism (parathyroid insufficiency).
  • Hyponatremia (sodium deficiency)
  • Hypothyroidism (hypothyroidism)
  • Malnutrition
  • Cushing’s disease – renal cortical hyperfunction with elevated cortisol levels.
  • Adrenal insufficiency
  • Niacin deficiency (nicotinic acid deficiency)
  • Vitamin B1 deficiency (thiamine)
  • Vitamin B12 deficiency (cobalamin)
  • Wernicke’s encephalopathy (synonyms: Wernicke-Korsakow syndrome; Wernicke’s encephalopathy) – degenerative encephaloneuropathic disease of the brain in adulthood; clinical picture: brain-organic psychosyndrome (HOPS) with memory loss, psychosis, confusion, apathy, as well as gait and stance unsteadiness (cerebellar ataxia) and eye movement disorders / eye muscle paralysis (horizontal nystagmus, anisocoria, diplopia)); vitamin B1 deficiency (thiamine deficiency).

Skin and subcutaneous (L00-L99).

  • Infections of skin/soft tissues, unspecified.

Cardiovascular system (I00-I99)

  • Apoplexy (stroke)
  • Heart failure (cardiac insufficiency)
  • Hypertensive encephalopathy – hypertensive emergency characterized by an increase in intracranial (inside the skull) pressure with consequent intracranial pressure signs.
  • Intracranial hemorrhage (bleeding within the skull; parenchymal, subarachnoid, sub- and epidural, and supra- and infratentorial hemorrhage)/intracerebral hemorrhage (ICB; cerebral hemorrhage), unspecified

Infectious and parasitic diseases (A00-B99).

  • Sepsis (blood poisoning)
  • Systemic infections, unspecified

Liver, gallbladder, and biliary tract – Pancreas (pancreas) (K70-K77; K80-K87).

Neoplasms – tumor diseases (C00-D48).

  • Gliomatosis cerebri – diffuse growths originating from specific cells of the nervous system.
  • Brain metastases – daughter tumors in the brain.
  • Brain tumor
  • Meningeosis carcinomatosa – occurrence of malignant infiltrates on the meninges.

Psyche – nervous system (F00-F99; G00-G99).

Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).

  • Hypothermia (hypothermia)
  • Uremia (occurrence of urinary substances in the blood above normal values).

Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).

  • Urinary tract infections, unspecified
  • Renal insufficiency (kidney weakness)

Injury, poisoning, and certain other sequelae of external causes (S00-T98).

Further

  • Hospitalization
  • Hyperthermia (overheating)
  • Hypoxia (tissue oxygen deficiency; respiratory/breath-related and cardiac/blood-related).
  • Immobility
  • Polypharmacy (> 6 prescribed medications).
  • Prefinal delirium – state of confusion in the context of near death.
  • Reduced sensory perceptions such as impaired vision, hearing, etc.
  • Poor general health

Medication

  • See “Causes” under medications

Environmental pollution – intoxications (poisoning).