Epilepsy as the cause of Dupuytren’s disease
Like diabetes, epilepsy is one of the associated diseases of Dupuytren’s disease. The correlation of the two diseases was first recognized in the 1940s and has been part of research ever since. The rate of new cases of Dupuytren’s contracture in epileptics can be up to 57%.
There is no correlation with regard to the respective severity. Nor does it make any difference what type of epilepsy is involved. There is also a discussion about the influence of drugs used in epilepsy therapy such as anticonvulsants on the development of Dupuytren’s contracture.
Furthermore, it is known that epileptics often develop ankle pads or fibrotic nodules under the foot, i.e. at the plantar aponeurosis. These are special forms of Dupuytren’s disease, so that a general tendency to restructure connective tissue towards fibrotic tissue is suspected in epilepsy. Everything about the topic “epilepsy” is listed below:
- Epilepsy – What you should consider
- Medication for epilepsy – Effects and side effects
Alcohol as the cause of Dupuytren’s disease
A precise explanation for the influence of alcohol consumption on the development of Dupuytren’s disease is not clear. There are various mechanisms that are being discussed. Among other things, it is assumed that the consumption of alcohol on the hands changes the blood circulation and causes damage to the fat and connective tissue.
In addition, long-term, heavy alcohol consumption can lead to the development of cirrhosis of the liver, which is known to be associated with Dupuytren’s disease. It is also assumed that in patients with liver cirrhosis, the formation of Dupuytren’s contracture is mostly due to alcohol consumption. In general, alcohol consumption alone or as part of cirrhosis of the liver increases the risk of developing Dupuytren’s disease.
Hyperlipidemia as a cause of Dupuytren’s disease
Hyperlipidemia is the presence of elevated blood lipids, including triglycerides and cholesterol. One can distinguish between different forms of hyperlipidemia depending on the distribution of the respective elevated fat components. The association of hyperlipidemia and Dupuytren’s disease is related to the diseases causing hyperlipidemia.
Both diabetes and increased alcohol consumption lead to an increase in blood lipid values. Since these two factors are in themselves risk factors or associated diseases for the development of Dupuytren’s contracture, hyperlipidemia is also considered a cause of Dupuytren’s disease.
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