To prevent alopecia (hair loss), attention must be paid to reducing individual risk factors. Behavioral risk factors
- Diet
- Malnutrition and malnutrition with accompanying micronutrient deficiency, see micronutrient therapy (vital substances) for details.
- Pleasure food consumption
- Tobacco (smoking)
- Smokers and ex-smokers were 80% more likely to suffer from alopecia androgenetica (androgen-induced hair loss) compared with nonsmokers of the same age; for heavy smokers who consumed more than 20 cigarettes per day, the risk was even increased by about 130%.
- Smoking and obesity → increased risk of alopecia androgenetica.
- Tobacco (smoking)
- Drug use
- Amphetamines (indirect sympathomimetic).
- Psycho-social situation
- Overweight (BMI ≥ 25; obesity) + smoking → risk increase for alopecia androgenetica.
X-rays
- Radiatio (radiotherapy)
Environmental pollution – intoxications (poisonings).
- Air pollutants: particulate matter (PM10) and diesel exhaust (→ decrease in the concentration of the protein beta-catenin in hair follicles; beta-catenin is required for hair growth).
Prevention factors (protective factors)
- Genetic factors
- Genetic risk depending on gene polymorphisms:
- Genes/SNPs (single nucleotide polymorphism):
- Genes: LINC01432
- SNP: rs1160312 in gene LINC01432
- Allele constellation: GG (0.625-fold for alopecia androgenetica).
- Genes/SNPs (single nucleotide polymorphism):
- Genetic risk depending on gene polymorphisms:
- Scalp cooling (“scalp cooling”) to prevent chemotherapy-induced hair loss; most common side effect is headache.