Clexane during pregnancy Pregnancy is an exceptional situation for the maternal body. Both positive and negative effects of pregnancy are possible. A thrombophilic tendency during pregnancy can be considered a negative effect. This means that blood clots are more likely to form. In the case of other risk factors and existing underlying diseases a therapy … Clexane during pregnancy | Clexane
Synonyms Active ingredient: enoxaparin, enoxaparin sodium, synonyms in the broader sense: low molecular weight heparin, Lovenox® English: enoxaparin sodium, low molecular weight heparins (LMWH) Definition Clexane® belongs to the group of medicinal anticoagulants. These anticoagulants are divided into: Clexane® belongs to the group of low-molecular-weight heparins, which comprises various substances that differ from unfractionated heparin … Clexane
Dosage form Clexane® is administered depending on the indication: Clexane® must not be injected into the muscles (i.m., intramuscularly). – Thrombosis prophylaxis = subcutaneous injection (into subcutaneous fatty tissue) Thrombosis therapy = subcutaneous injection Non-suspension infarction (NSTEMI) /instable angina pectoris = subcutaneous injection Elevation myocardial infarction (STEMI) = first intravenous bolus administration, then subcutaneous injection … Dosage form | Clexane
Pharmacokinetics After subcutaneous injection of Clexane®, it enters the bloodstream where it reaches its average maximum activity level after three to five hours. Clexane® is broken down both in the liver (hepatic elimination) and in the kidney (renal elimination), with the majority being taken over by the liver. The plasma half-life – the time after … Pharmacokinetics | Clexane
Synonyms in a broader sense Phenprocoumon (active ingredient name), coumarins, vitamin K antagonists (inhibitors), anticoagulants, anticoagulants What are alternatives to Marcumar®? The commercial product Pradaxa® contains the active ingredient dabigatran etexilate. The active ingredient is a direct thrombin inhibitor. This means that it directly and reversibly inhibits so-called thrombin. Thrombin plays an important role in … Alternatives to Marcumar®
Xarelto® The commercial product Xarelto® contains the active ingredient rivaroxaban. It is a direct and reversible inhibitor of coagulation factor 10, which also plays a very important role in blood coagulation. The indications are similar to those for other blood-clotting inhibitors. Rivaroxaban has a half-life of 7-11 hours. This makes it more flexibly controllable. Under … Xarelto® | Alternatives to Marcumar®
Marcumar® contains the active ingredient phenprocoumon and is an anticoagulant drug belonging to the group of coumarins and vitamin K antagonists. It inhibits the vitamin K-dependent formation of the coagulation factors II, VII, IX and X, which takes place in the liver. Furthermore, Marcumar® suppresses the formation of protein C and S, which serve as … Marcumar® and alcohol – is it compatible?
Side effects and interactions In principle, the use of Marcumar® does not necessarily speak against moderate, occasional consumption of alcohol. However, in view of the very complex influence of alcohol on the effect of Marcumar®, its consumption should be avoided. Moderate and occasional consumption of alcohol includes consumption of less than 12 grams of pure … Side effects and interactions | Marcumar® and alcohol – is it compatible?
Nutrition when taking Marcumar® When taking Marcumar, some special dietary requirements should be taken into account. As with many medications, Marcumar is absorbed more slowly in the stomach if it is filled with food at the same time. The required effect level, i.e. the minimum amount of a drug in the blood that must be … Nutrition when taking Marcumar® | Marcumar® and alcohol – is it compatible?
Synonyms in a broader sense Phenprocoumon (active ingredient name) Coumarins Vitamin K antagonists (inhibitors) Anticoagulants Anticoagulant Side effects of Marcumar Side effects (so-called UAW’s, adverse drug reactions) and interactions with other drugs Among the most common undesirable effects of coumarin therapy are lighter bleeding with haematoma. These are usually harmless (2-5% of patients), so discontinuing … Side effects of Marcumar
When must Marcumar® not be given? In general, coumarins must not be administered during pregnancy, as they can cause severe damage both in the early stages of child development (“embryopathies”, third to eighth week of pregnancy) and in the later, usually less sensitive developmental stages (“fetopathies”, from the ninth week of pregnancy onwards). Alternatives to … When must Marcumar® not be given? | Side effects of Marcumar
Definition Heparin belongs to the group of anticoagulants (blood clotting inhibitors). It is a molecule produced in the human and animal organism and is used, among other things, for the prevention (avoidance) of thrombosis (formation of blood clots with dislocation of blood vessels and subsequent reduced blood supply to organs). Blood Coagulation Greek. Hemostasis of … Heparin
