Acne: Causes

Pathogenesis (development of disease) Acne vulgaris is a chronic inflammatory disease of the sebaceous glands. Acne is caused by changes in the skin due to hormonal influences such as those that occur during puberty (androgen production ↑). IGF-1 (insulin-like growth factor 1) seems to be important for the stimulation of androgen signaling. IGF-1 increases the … Acne: Causes

Acne: Classification

Classification an acne vulgaris in degrees of severity according to the number of papules and pustules. Severity Description Grade I <10 papules and pustules/half of face Grade II 10 to 20 papules and pustules/half of face Grade III 20 to 30 papules and pustules/half of face Grade IV > 30 papules and pustules/half of face … Acne: Classification