The INR (International Normalized Ratio) value is a laboratory parameter that describes blood clotting. To determine the INR value, blood tests measure the time it takes for the blood to clot (called the thromboplastin time or TPZ). Along with the determination of the Quick value, the INR is the second way of expressing the TPZ. … International Normalized (INR)
PTT (partial thromboplastin time) is a control parameter of blood clotting. The name PTT is actually obsolete because today the test is performed with the addition of a contact activator, in contrast to an earlier variant. The current designation is therefore activated partial thromboplastin time (aPTT). As a so-called global test of plasmatic blood coagulation, … Partial Thromboplastin Time (PTT)
The Quick value (synonyms: thromboplastin time, TPZ; prothrombin time, PTZ) is a laboratory parameter that describes blood clotting. As a so-called global test of plasmatic blood coagulation, the Quick test records several reaction steps of blood coagulation, including the binding ability of the coagulation factors to phospholipid surfaces. It detects the activity of factors II, … Quick Value Explained
The thrombin time (TC; synonyms: plasma thrombin time, plasma thrombin time; PTZ; thrombin clotting time (TCT), thrombin time, TT) occupies a special position in coagulation diagnostics. It measures the last step in the coagulation cascade, namely fibrin polymerization (process of fibrin stabilization). Thrombin time measures the conversion of fibrinogen (factor I) to fibrin by addition … Thrombin Time
Von Willebrand-Jürgens factor (vWF; synonyms: Clotting factor VIII-associated antigen or von Willebrand factor antigen, vWF:Ag) is an adhesive glycoprotein (macromolecules consisting of a protein and one or more covalently bound carbohydrate groups (sugar groups)) that plays an important role in hemostasis (blood clotting). It is involved in primary and secondary hemostasis. In primary hemostasis, it … Von Willebrand-Jürgens Factor
Bleeding time (BZ) is the time that elapses after artificial placement of a bleeding injury until hemostasis (“hemostasis”) occurs. It is a test for the orientational assessment of primary hemostasis. Procedures Duke bleeding time: placing a lancet puncture at the edge of the earlobe.Without touching the wound, the blood that flows out is removed every … Bleeding Time
Since butD-dimers are so-called fibrin cleavage products. These are formed in fibrinolysis (dissolution of blood clots) from cross-linked fibrin. They have a half-life of about eight hours.D-dimer can be used as a reliable test in cases of suspected thrombosis or pulmonary embolism, but precise localization of the event is not possible with this method. Other … D-dimers: What are they?
Factor VIII (synonym: antihemophilic globulin A) is one of the coagulation factors. Defects affecting factor VIII are usually inherited in an X-linked recessive manner. Men are affected with a probability of 1:6,000 and are then referred to as hemophilia A (hemophilia). There is a reduced synthesis of the clotting factor or abnormal proteins are produced. … Factor VIII: Antihemophilic Globulin A