Products Benralizumab was approved as a solution for injection in the United States in 2017 and in the EU and many countries in 2018 (Fasenra). Structure and properties Benralizumab is a humanized and afucosylated IgG1κ antibody with a molecular mass of 150 kDa. It is produced by biotechnological methods. Omission of the fucose in the … Benralizumab
Products and ingredients Inhalation solution B is not commercially available as a finished drug in many countries and must be prescribed by a physician as an extemporaneous prescription and prepared in a pharmacy. In practice, different manufacturing prescriptions are used with the pure substances or the solutions. Dospir and Ipramol have a similar composition, but … Inhalation Solution B
Products Reslizumab was approved in the United States and EU in 2016 and in many countries in 2017 as a concentrate for the preparation of an infusion solution (Cinqaero). Structure and properties Reslizumab is a humanized IgG4/κ monoclonal antibody produced by biotechnological methods. The molecular mass is approximately 147 kDa. Effects Reslizumab (ATC R03DX08) binds … Reslizumab
Products Zafirlukast was commercially available in the form of film-coated tablets (Accolate, off label). It was approved in many countries in 1998. It was discontinued from distribution in 2019. Montelukast is a suitable substitute. Structure and properties Zafirlukast (C31H33N3O6S, Mr = 575.7 g/mol) exists as a fine, white to pale yellow, amorphous powder that is … Zafirlukast
Products Mepolizumab was approved in the US and EU in 2015 and in many countries in 2016 in the form of a solution for injection (Nucala). Structure and properties Mepolizumab is a humanized IgG1κ monoclonal antibody with a molecular mass of 149 kDa produced by biotechnological methods. Effects Mepolizumab (ATC R03DX09) has anti-inflammatory and antiasthmatic … Mepolizumab
Products Leukotriene antagonists are commercially available as film-coated tablets, granules, and chewable tablets. Structure and properties The active ingredients do not have a uniform chemical structure. Effects The leukotriene antagonists (ATC R03DC) have antiasthmatic, anti-inflammatory, bronchodilator, and antiallergic properties. They bind to the CysLT1 receptor, thereby inhibiting the effects of the cysteinyl leukotrienes LTC4, LTD4, … Leukotriene Antagonists
Effects Leukotriene synthesis inhibitors are antiallergic and anti-inflammatory. Mechanism of action Inhibition of the synthesis of leukotrienes from arachidonic acid by inhibition of 5-lipoxygenase. Indications For prevention and long-term therapy of asthma in adults and children over 12 years of age. Active ingredients Zileuton (USA: Zyflo) – not commercially available in many countries.
Display Folium Belladonnae 2 T. Folium Stramonii 4 T. Herba Lobeliae 2 T. Potassium nitricum 2 T. Aqua 5 T. The potassium nitrate is dissolved in warm water and the solution is added to the drug powder mixture, to which unadjusted rabi is to be added. Once the powder is uniformly saturated by the potassium … Pulvis Stramonii Compositus (Asthma Powder)
Products Montelukast is commercially available as film-coated tablets and as granules and chewable tablets for children (Singulair, generic). It has been approved in many countries since 1998. Structure and properties Montelukast (C35H36ClNO3S, Mr = 586.18 g/mol) is a chloroquinoline derivative. It is present in drugs as montelukast sodium, a white crystalline powder that is readily … Montelukast
Products Theophylline is commercially available as sustained-release tablets and as an injectable (Unifyl, Aminophylline). It has been approved in many countries since 1954. Euphylline is no longer marketed. Structure and properties Theophylline (C7H8N4O2, Mr = 180.2 g/mol) is a white crystalline powder that is sparingly soluble in water. It is a methylxanthine and structurally related … Theophylline: Drug Effects, Side Effects, Dosage and Uses
Products Clenbuterol is not commercially available as a human drug in many countries, but exclusively as a veterinary drug for the treatment of respiratory diseases (e.g., Ventipulmin ad us vet). It is available only on medical prescription. In other countries, clenbuterol is on the market in tablet and drop form (Spiropent). Structure and properties Clenbuterol … Clenbuterol