Introduction Humira is the trade name for the biological Adalimumab, which is used for the treatment of for example rheumatoid arthritis and other rheumatic diseases, psoriasis and chronic inflammatory intestinal diseases. It is injected under the abdominal skin every two weeks. Remarkable is beside its various application also its price: One application costs approx. 1000€. … Humira
Active ingredient and effect As mentioned above, adalimumab is an antibody against the pro-inflammatory tumor necrosis factor alpha (TNF-α). The TNF-α causes the release of many other inflammatory messengers in the body; one could say that it fires up the inflammation.It is therefore elevated in the blood in many diseases that are associated with an … Active ingredient and effect | Humira
Interactions Humira is often used in combination with cortisone, with methotrexate, which is also an immune-inhibiting drug, or in combination with other specified drugs with similar effects. An exception are the active substances Etanacept, Abatacept and Anakinra, among which in combination with Humira among other things heavy infections and increased side effects could be proven. … Interactions | Humira
Why are the costs so high? As explained above, Humira is a biological agent, i.e. a drug that is produced biotechnologically using genetically modified organisms. In the case of Humira, these are so-called CHO cells (Chinese hamster ovaries). This means that the eggs of the Chinese hamster are used to produce the antibody Adalimumab. As … Why are the costs so high? | Humira