Dextromethorphan: Effects and Applications
How dextromethorphan works Dextromethorphan suppresses the cough reflex by depressing the cough center in the brainstem. It does this by blocking (antagonizing) the so-called NMDA receptors and by triggering signals (agonism) at sigma-1 receptors. By interacting with NMDA receptors, dextromethorphan can suppress the perception of pain. For this reason, the active ingredient has also been … Dextromethorphan: Effects and Applications
