Products Deferasirox is commercially available in the form of film-coated tablets (Jadenu, generic). It was approved in many countries in 2005. Exjade is no longer marketed. Structure and properties Deferasirox (C21H15N3O4, Mr = 373.4 g/mol) Effects Deferasirox (ATC V03AC03) is an orally active chelator with high selectivity for trivalent iron. It is a three-armed ligand … Deferasirox
Products Deferiprone is commercially available in the form of film-coated tablets (Ferriprox, generic). It was approved in many countries in 2001. Structure and properties Deferiprone, or 3-hydroxy-1,2-dimethylpyridin-4-one (C7H9NO2, Mr = 139.2 g/mol) is a methylated and hydroxylated pyridinone derivative. It belongs to the α-ketohydroxypyridones. Deferiprone exists as a white to pink crystalline powder that is … Deferiprone
Products Deferoxamine is commercially available as an injectable (Desferal). It has been approved in many countries since 1963. Structure and properties Deferoxamine is present in drugs as deferoxamine mesilate (C26H52N6O11S, Mr = 657 g/mol), a white powder that is readily soluble in water. Effects Deferoxamine (ATC V03AC01) forms complexes with trivalent iron and aluminum and … Deferoxamine
