Multi-Kinase Inhibitors

Sorafenib

Products Sorafenib is commercially available in the form of film-coated tablets (Nexavar). It has been approved in many countries since 2006. Structure and properties Sorafenib (C21H16ClF3N4O3, Mr = 464.8 g/mol) is present in drugs as sorafenibtosilate, a white to yellowish or brownish powder that is practically insoluble in water. Effects Sorafenib (ATC L01XE05) has antiproliferative, … Sorafenib

Lenvatinib

Products Lenvatinib was approved in many countries in 2015 in capsule form (Lenvima). In 2017, Kisplyx capsules were also approved. Structure and properties Lenvatinib (C21H19ClN4O4, Mr = 426.9 g/mol) is present in the drug as lenvatinib mesilate, a white to pale reddish-yellow powder that is sparingly soluble in water. It is a quinoline and carboxamide … Lenvatinib