Quinolones

Enoxacin

Products Enoxacin is commercially available in the form of film-coated tablets (Enoxor). The drug is not registered in many countries. Structure and properties Enoxacin (C15H17FN4O3, Mr = 320.3 g/mol) is a fluoroquinolone. Effects Enoxacin (ATC J01MA04) has bactericidal properties. The effects are due to inhibition of bacterial DNA gyrase. Indications For the treatment of infections … Enoxacin

Nadifloxacin

Products Nadifloxacin is commercially available as a cream (Nadixa). The drug is not registered in many countries. It has been approved in Japan since 1993 and in Germany since 2000. Structure and properties Nadifloxacin (C19H21FN2O4, Mr = 360.4 g/mol) is a 3rd generation fluoroquinolone. The figure shows the more active -nadifloxacin; the cream contains the … Nadifloxacin