Products Medicines containing Caroverin are currently no longer available in many countries. Calmavérine is out of commerce. Structure and properties Caroverin (C22H27N3O2, Mr = 365.5 g/mol) Effects Caroverin (ATC A03AX11) is spasmolytic on smooth muscle with predominantly musculotropic effects. Indications Spasms of the gastrointestinal tract, biliary tract, urinary tract, and female genital tract in dysmenorrhea. … Caroverin
Products In many countries, finished drug products containing papaverine are no longer on the market. Spasmosol (combination) is no longer available. Structure and properties Papaverine (C20H21NO4, Mr = 339.4 g/mol) is present in drugs as papaverine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a natural alkaloid found in the … Papaverine
Products Salverin is no longer on the market in many countries. Structure and properties Salverine (C19H24N2O2, Mr = 312.4 g/mol) is a phenylbenzamide derivative. In drugs, it is present as salverine hydrochloride. Effects Salverine has antispasmodic and mild depressant properties. It is a papaverine-type spasmolytic without atropine-like effects. Indications For the treatment of smooth muscle … Salverin
Products Pinaverium bromide is commercially available in the form of film-coated tablets (Dicetel). It has been approved in many countries since 1985. Structure and properties Pinaverium bromide (C26H41Br2NO4, Mr = 591.4 g/mol) Effects Pinaverium bromide (ATC A03AX04) is antispasmodic with selective action on the digestive tract. It is a calcium antagonist and inhibits calcium influx … Pinaverium Bromide
Products Drofenine is registered for export in tablet form (Lunadon, combination). It has been approved in many countries since 1977 but is not commercially available. Structure and properties Drofenine (C20H31NO2, Mr = 317.47 g/mol) is a derivative of atropine. It exists as drofenine hydrochloride, a white, loose crystalline powder that is very soluble in water. … Drofenin
Products Mebeverine is commercially available in the form of sustained-release capsules (Duspatalin Retard). It has been approved in many countries since 1967. Structure and properties Mebeverine (C25H35NO5, Mr = 429.6 g/mol) is an open-chain derivative of papaverine. It is present in drugs as mebeverine hydrochloride, a white crystalline powder that is very soluble in water. … Mebeverin
Products Flavoxate is commercially available in the form of film-coated tablets (Urispas). It has been approved in many countries since 2008. Structure and properties Flavoxate (C24H25NO4, Mr = 391.5 g/mol) is present in drugs as flavoxate hydrochloride, an oxo-benzopyran and piperidine derivative. An active metabolite is involved in the effects. Effects Flavoxate (ATC G04BD02) has … Flavoxat