Uricosuric Drugs

Sulfinpyrazone

Products Anturan dragées are no longer on sale in many countries. Structure and properties Sulfinpyrazone (C23H20N2O3S, Mr = 404.5 g/mol) is a white powder that is sparingly soluble in water. Effects Sulfinpyrazone (ATC M04AB02) is uricosuric and antiplatelet. Indications Gout Reinfarct prophylaxis Thrombosis prophylaxis

Lesinurad

Products Lesinurad was approved in the US in 2015, in the EU in 2016, and in many countries in 2017 in film-coated tablet form (Zurampic). A fixed-dose combination with allopurinol was released in the US in 2017 (Duzallo), in the EU in 2018, and in many countries in 2019. Structure and properties Lesinurad (C17H14BrN3O2S, Mr … Lesinurad