Lipid Metabolism Disorders (Hyperlipoproteinemias): Classification
Primary and secondary hyperlipoproteinemias can be distinguished: I. Primary hyperlipoproteinemias (HLP) Primary hypercholesterolemia Form Description Incidence Distribution of fats Familial hypercholesterolemia (FH) Autosomal-dominantly inherited defect of the LDL receptor Homozygous form: 1: 250,000 to 1: 1,000,000. Heterozygous form: about 1: 500 LDL ↑ Autosomal recessive hypercholesterolemia Mutations in the LDLRAP1 gene with impaired uptake of … Lipid Metabolism Disorders (Hyperlipoproteinemias): Classification
