Medical history (history of illness) is an important component in the diagnosis of pancreatic insufficiency (pancreatic insufficiency). Family history Are there any diseases of the digestive system in your family that are common? Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history (somatic and … Pancreatic Insufficiency: Medical History
Endocrine, nutritional, and metabolic diseases (E00-E90). Cystic fibrosis (ZF) – genetic disorder with autosomal recessive inheritance characterized by the production of secretions in various organs that need to be tamed. Liver, gallbladder and bile ducts – pancreas (pancreas) (K70-K77; K80-K87). Chronic pancreatitis – chronic inflammation of the pancreas. Neoplasms – tumor diseases (C00-D48) Pancreatic carcinoma … Pancreatic Insufficiency: Or something else? Differential Diagnosis
1st-order laboratory parameters-obligatory laboratory tests. Small blood count Differential blood count Elastase in the stool (protein-cleaving enzyme of the pancreas) [only meaningful in moderate or severe pancreatic insufficiency]. Fasting glucose (fasting blood glucose). Electrolytes – calcium, potassium and magnesium (hypomagnesemia (magnesium deficiency) in exocrine pancreatic insufficiency/disease of the pancreas referred to insufficient production of digestive … Pancreatic Insufficiency: Test and Diagnosis
Therapeutic goals or recommendations In exocrine pancreatic insufficiency (disease of the pancreas associated with insufficient production of digestive enzymes): Substitution (“replacement”) of the missing enzymes (see below pancreatic enzymes). Endocrine pancreatic insufficiency (disease of the pancreas associated with insufficient production of hormones, specifically insulin and glucagon): Achieving stable glucose controlThe endocrine pancreatic insufficiency is treated … Pancreatic Insufficiency: Drug Therapy
Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnosticsand obligatory medical device diagnostics – for differential diagnostic clarification. Abdominal ultrasonography (ultrasound examination of the abdominal organs) – for basic diagnostics. Computed tomography (CT) of the abdomen (abdominal CT) – to exclude malignant (malignant) diseases or complicating courses. Magnetic … Pancreatic Insufficiency: Diagnostic Tests
To prevent pancreatic insufficiency (pancreatic insufficiency), attention must be paid to reducing individual risk factors. Behavioral risk factors Diet Malnutrition – low protein (low protein) diet. Pleasure food consumption Alcohol (abuse)
The following symptoms and complaints may indicate pancreatic insufficiency (pancreatic insufficiency): Leading symptoms Steatorrhea (fatty stools). Hypocholesterolemia – decrease in blood cholesterol levels. Diarrhea (diarrhea) Unintentional weight loss Diabetes mellitus (diabetes) Associated symptoms Bleeding tendency Night blindness Acrodermatitis – inflammatory skin disease of the end limbs of the body such as fingers and toes. Meteorism … Pancreatic Insufficiency: Symptoms, Complaints, Signs
Pathogenesis (development of disease) The pancreas (pancreas) has two important functions, an exocrine function and an endocrine function. First, it produces various digestive enzymes such as trypsinogen, amylase, and lipase. These are then released into the duodenum (duodenum) (= exocrine function). In addition to this exocrine function, the pancreas produces the vital hormones insulin and … Pancreatic Insufficiency: Causes
General measures Alcohol restriction (abstaining from alcohol), for life! Nicotine restriction (abstaining from tobacco use). Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance analysis and, if necessary, participation in a medically supervised program for the underweight. Falling below the BMI lower limit … Pancreatic Insufficiency: Therapy
The following are the most important diseases or complications that may be contributed to by pancreatic insufficiency (pancreatic insufficiency): Endocrine, nutritional, and metabolic diseases (E00-E90). Diabetes mellitus Vitamin D deficiency Infectious diseases, unspecified Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93). Dysbiosis (imbalance of intestinal flora). Musculoskeletal system and connective tissue (M00-M99). Osteoporosis (bone … Pancreatic Insufficiency: Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye) [acrodermatitis – inflammatory skin disease of the body’s end limbs such as fingers and toes]. Auscultation (listening) of the … Pancreatic Insufficiency: Examination
