The following are the most important diseases or complications that may be contributed to by HLA-B27-associated reactive arthritis:
Mouth, esophagus (food pipe), stomach, and intestine (K00-K67; K90-K93).
- Chronification of joint symptoms
- Ankylosing spondylitis (ankylosing spondylitis) – chronic inflammatory rheumatic disease associated with pain and stiffness of the spine.