Latent (subclinical) hypothyroidism (SCH; synonyms: compensated hypothyroidism; latent hypothyroidism; latent hypothyroidism; latent hypothyroidism; subclinical hypothyroidism; ICD-10-GM E03. 9: Hypothyroidism, unspecified) refers to a “mild” hypothyroidism that is usually manifested only by a change in the thyroid parameter TSH: TSH > 4 mU/l, with a concomitant normal fT4 level. If TSH is higher than 10 mU/L … Latent Hypothyroidism
Medical history (history of illness) represents an important component in the diagnosis of latent (subclinical) hypothyroidism (hypothyroidism). Family history Is there a frequent history of thyroid disease in your family? Are there any hereditary diseases in your family? Social anamnesis Current medical history/systemic medical history (somatic and psychological complaints). What symptoms have you noticed? Depressive … Latent Hypothyroidism: Medical History
Endocrine, nutritional, and metabolic diseases (E00-E90). Struma multinodosa – nodular change in thyroid tissue. Cardiovascular system (I00-I99) Heart failure (cardiac insufficiency) Neoplasms – tumor diseases (C00-D48) Thyroid carcinoma – malignant neoplasm of the thyroid gland. Medication Chronic iodine excess mainly triggered by drugs (especially amiodarone – drug for cardiac arrhythmias).
The following are the major conditions or complications that may be contributed to by latent (subclinical) hypothyroidism (hypothyroidism): Certain conditions originating in the perinatal period (P00-P96). Neurologic damage in the fetus Endocrine, nutritional, and metabolic diseases (E00-E99). Diabetes mellitus type 2 Increase of the homocysteine level Hypercholesterolemia (increased levels of cholesterol in the blood; LDL … Latent Hypothyroidism: Complications
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye). Inspection and palpation (palpation) of the thyroid gland and lymph nodes [due todifferential diagnosis: struma multinodosa – nodular change … Latent Hypothyroidism: Examination
1st-order laboratory parameters-obligatory laboratory tests. TSH (thyroid-stimulating hormone)* [TSH level > 4 mU/l → repeat measurement for confirmation]. FT4 (thyroxine) [within normal range] * Latent hypothyroidism: TSH value > 4 mU/l + fT4 in the normal range. Note: In latent hypothyroidism, thyroid levels are determined again after 4-8 weeks. 2nd order laboratory parameters – depending … Latent Hypothyroidism: Test and Diagnosis
In latent hyperthyroidism (latent hyperthyroidism) or subclinical hyperthyroidism, symptoms or complaints occur only very diffusely. The following symptoms and complaints may indicate latent (subclinical) hyperthyroidism: Palpitations (heart palpitations) Cardiac arrhythmias such as atrial fibrillation (VHF) or sinus tachycardia (> 100 heartbeats/minute). Decreased resilience Tremor (shaking) Hyperhidrosis – increased sweating. Heat intolerance Anxiety Nervousness Concentration problems … Latent Hyperthyroidism: Symptoms, Complaints, Signs
In hyperthyroidism (synonyms: Hyperthyroidism; Hyperthyroidism; Thyroid hormone toxicity; Hyperthyroidism; Thyrotoxicosis; ICD-10-GM E05.9: Hyperthyroidism, unspecified) is hyperthyroidism due to multiple causes. The most important cause is Graves’ disease, which is responsible for 60-80% of all hyperthyroidism. Other causes include thyroid autonomy (independent thyroid hormone production) and iodine-induced hyperthyroidism (exogenous intake of iodine in high amounts). Hyperthyroidism … Hyperthyroidism (Overactive Thyroid)
Medical history (history of illness) represents an important component in the diagnosis of hyperthyroidism (hyperthyroidism). Family history Is there a frequent history of thyroid disease in your family? Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history (somatic and psychological complaints). What symptoms have … Hyperthyroidism (Overactive Thyroid): Medical History
Endocrine, nutritional, and metabolic diseases (E00-E90). Autoimmune thyroiditis (Hashimoto’s thyroiditis) – autoimmune disease of the thyroid gland; initially with increased secretion of thyroid hormones, later with gradual transition to hypothyroidism (hypothyroidism). Hyperthyroidism with decreased or absent uptake in the thyroid scintigram. Hyperthyroidism factitia – overdose of thyroid hormones. Marine-Lenhart syndrome – simultaneous occurrence of nodular … Hyperthyroidism (Overactive Thyroid): Or something else? Differential Diagnosis
The following are the most important diseases or complications that can be caused by hyperthyroidism (overactive thyroid): Eyes and eye appendages (H00-H59). Corneal damage due to dehydration in the absence/incomplete closure of the eyelids. Optic nerve compression – high pressure on the optic nerve can lead to visual impairment or blindness Endocrine, nutritional, and metabolic … Hyperthyroidism (Overactive Thyroid Gland): Complications
Hyperthyroidism is classified according to symptoms into: Subclinical (latent) hyperthyroidism – asymptomatic (with no apparent symptoms). Clinical hyperthyroidism – hyperthyroidism associated with symptoms. Hyperthyroidism is classified according to the location of the disorder into: Primary hyperthyroidism – “true” hyperthyroidism. Manifest form – elevation of free triiodothyronine (fT3) and/or free thyrosine (fT4) above the upper normal … Hyperthyroidism (Overactive Thyroid): Classification
