Synonyms in the broadest sense Brittle bone disease, congenital bone fragility, fragilitas osseum Definition Osteogenesis imperfecta (brittle bone disease) is a congenital disorder of the collagen balance. Collagen is a structure of the connective tissue. This makes the bones abnormally brittle. The gene mutation affects not only bones, but also tendons, ligaments, teeth and the … Osteogenesis imperfecta
Special feature The fractures are usually observed in the affected children until puberty. However, the greatest frequency of fractures seems to be in the first growth spurt at about 5 – 8 years of age. After puberty, the fractures stop. The disease can manifest itself differently in each affected person. Osteogenesis imperfecta (brittle bone disease) … Special feature | Osteogenesis imperfecta
Prophylaxis The actual disease cannot be avoided, only the bone fractures can be tried to prevent. Orthoses and splints can be used for this purpose. Orthoses are bone splints made of plastic in which, for example, the leg is embedded. The word probably originated from the words “orthopedic” and “prosthesis”. Orthoses are used for the … Prophylaxis | Osteogenesis imperfecta
