Subclinical Inflammation: Prevention

To prevent subclinical inflammation (silent inflammation), attention must be paid to reducing individual risk factors.

Behavioral risk factors

  • Diet
    • Increased intake of saturated fatty acis (SFA).
    • Increased intake of foods with high glycemic index → increase in NF-κB activation and NF-κB binding in mononuclear cells.
    • Consumption of contaminated foods (e.g., pesticides, heavy metals, etc.).
    • Consumption of processed food / processed food (eg, food additives).
    • Micronutrient deficiency (vital substances) – see prevention with micronutrients.
  • Consumption of stimulants
    • Tobacco (smoking)
  • Physical activity
    • Extreme physical work
  • Psycho-social situation
    • Stress
  • Overweight (BMI ≥ 25; obesity).
  • Android body fat distribution, i.e., abdominal/visceral, truncal, central body fat (apple type) – there is a high waist circumference or waist-to-hip ratio (THQ; waist-to-hip-ratio (WHR)); see “Adipose tissue as an endocrine organ” – esp. Fetuin A, tumor necrosis factor (TNF-alpha), IL-6, and other cytokinesWhen measuring waist circumference according to the International Diabetes Federation guideline (IDF, 2005), the following standard values apply:
    • Men <94 cm
    • Women < 80 cm

    The German Obesity Society published somewhat more moderate figures for waist circumference in 2006: < 102 cm for men and < 88 cm for women.

X-rays

  • Radiatio (radiotherapy)
  • Ionizing rays

Environmental pollution – Intoxications (poisoning).

  • Particulate matter
  • Hazardous working materials
  • Plastics
  • Pesticides / insecticides
  • Heavy metals