A comprehensive clinical examination is the basis for selecting further diagnostic steps:
- General physical examination – including blood pressure, pulse, body temperature, body weight, body height; furthermore:
- Inspection (viewing).
- Skin, mucous membranes, and sclerae (white part of the eye) [accompanying symptoms: night sweats; pruritus (itching); pallor; erythema nodosum (nodular erythema), localization: both extensor sides of the lower leg, on the knee and ankle joints; less commonly on the arms or buttocks]
- Abdomen (abdomen)
- Shape of the abdomen?
- Skin color? Skin texture?
- Efflorescences (skin changes)?
- Pulsations? Bowel movements?
- Visible vessels?
- Scars? Hernias (fractures)?
- Inspection and palpation (palpation) of lymph node stations (cervical, axillary, supraclavicular, inguinal, mediastinal, abdominal) [Leading symptom: painless lymphadenopathy (lymph node enlargement) (lymph nodes caked into packets] [Concomitant symptom: lymph node swelling after consumption of alcohol.]
- Auscultation (listening) of the heart
- Auscultation of the lungs [accompanying symptom: irritable cough].
- Examination of the abdomen (belly)
- Inspection (viewing).
- If necessary, urological/nephrological examination [due topossible secondary disease: nephrotic syndrome – collective term for symptoms that occur in various diseases of the glomerulus (renal corpuscles); symptoms are: Proteinuria (increased excretion of protein in the urine) with a protein loss of more than 1 g/m²/body surface per day; Hypoproteinemia, peripheral edema (water retention) due to a hypalbuminemia of < 2.5 g/dl in serum, hyperlipoproteinemia (lipid metabolism disorder)]
- Health check (as an additional follow-up measure).
Square brackets [ ] indicate possible pathological (pathological) physical findings.