Ichthyosis: Complications

The following are the most important diseases or complications that may be contributed to by ichthyosis:

Eyes and eye appendages (H00-H59).

  • If an ectropion is present, the following diseases may occur:
    • Epiphora – leakage of tear fluid over the edge of the eyelid.
    • Keratitis (inflammation of the cornea)
    • Keratoconjunctivitis sicca (dry eyes)
    • Conjunctivitis (conjunctivitis)

Endocrine, nutritional and metabolic diseases (E00-E90).

  • Vitamin D deficiency

Skin and subcutaneous tissue (L00-L99)

  • Rhagades (fissures; narrow, cleft-shaped tear that cuts through all layers of the epidermis (cuticle)).

Infectious and parasitic diseases (A00-B99).

  • Bacterial skin infections
  • Sepsis (blood poisoning)

Further

  • Protein and water loss due to desquamation
  • Sweating disorder, possibly with hyperpyrexia (extreme fever: higher than 41 °C) – due to the cornifications, the sweating of the skin is disturbed (anhidrosis)